Background: Multidisciplinary aortic programs integrate advanced imaging, standardized clinical pathways, procedural expertise, and longitudinal surveillance. We evaluated the evolution and outcomes of endovascular aortic care at Vietnam National Heart Institute (VNHI), Bach Mai Hospital, using institutional TEVAR and EVAR cohorts and the prospective VNHI Aortic Registry through June 2026. Methods: Single-center observational report drawing on two historical institutional endovascular cohorts (TEVAR from January 2014 to December 2020, n=102; EVAR from January 2019 to August 2025, n=235) and a prospectively maintained registry (January-June 2026, n=96) in the VNHI Aortic Registry, Bach Mai hospital. Cohorts were summarized separately because enrollment periods, disease profiles, and follow-up differed. Outcomes were analyzed within each source cohort. Prespecified outcomes included technical success, perioperative mortality, major procedure-related complications, aortic remodeling, secondary reintervention, and mid-term survival. Results: Technical success was 100/102 (98.0%) TEVAR and 235/235 (100%) EVAR cases. In-hospital mortality was 3/102 (2.9%) in the dedicated TEVAR cohort; 30-day mortality was 2/235 (0.9%) in the EVAR cohort. Spinal cord ischemia occurred after TEVAR in 5/102 (4.9%) patients; all affected patients recovered before discharge following a standardized rescue protocol. Thoracic aortic coverage ≥ 270 mm was independently associated with spinal cord ischemia (odds ratio, 10.11; 95% confidence interval, 1.41-72.55; P=0.021). In the historical TEVAR source, complete false-lumen thrombosis in the covered thoracic segment was reported in 87.1% at 12 months; the imaging denominator remains to be confirmed. Estimates of long-term survival and regression-derived associations are withheld from this abstract pending verification of follow-up dates, numbers at risk, and model specifications. The 2026 registry contains 96 recorded entries but is not treated as an additional independent patient cohort until overlap is assessed. Four-year cumulative survival was 87.9% TEVAR and 84.6% EVAR; secondary reintervention occurred in 3.9% and 4.3%, respectively. Conclusions: A structured multidisciplinary endovascular aortic program at VNHI was associated with high technical success and favorable mid-term outcomes in selected patients undergoing TEVAR or EVAR. These findings support the feasibility of organized aortic care in an emerging healthcare system; however, prospective risk-adjusted evaluation is required to determine the independent effect of the program on clinical outcomes. Complete patient-level reconciliation and standardized longitudinal surveillance are necessary for robust benchmarking.
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