Key result
High-frequency ultrasonography differentiates superficial from subcutaneous cutaneous myxomas based on margin and echogenicity features.
Why the study?
Cutaneous myxomas usually precede cardiac myxomas in Carney complex, and although high-frequency ultrasonography plays an essential role in their differential diagnosis, the ultrasonographic features of superficial and subcutaneous cutaneous myxomas had not previously been described in the literature.
Case Report (n=1)
No
May offer noninvasive clues for cutaneous myxomas in Carney complex; leaves open validation in larger cohorts before clinical use.
Carney complex is a rare genodermatosis characterized by cardiac and cutaneous myxomas, among other tumors. In the majority of cases, cutaneous myxomas precede the diagnosis of cardiac myxomas, which are the main cause of death in these patients. Despite the fact that the diagnosis of cutaneous myxomas is histopathological, high-frequency ultrasonography plays an essential role in the differential diagnosis with other cutaneous and subcutaneous tumors. The authors of the present study describe, for the first time in the literature, the ultrasonographic features of both variants of cutaneous myxomas, superficial and subcutaneous, in a patient with a Carney complex.
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Quintana‐Codina et al. (2021) conducted a case report in Carney complex with cutaneous myxomas (n=1). High-frequency ultrasonography (10-18 MHz) vs. Histopathology was evaluated on Ultrasonographic characterization of superficial and subcutaneous cutaneous myxomas. High-frequency ultrasonography showed superficial myxomas as well-defined, homogeneous hypoechoic dermal lesions and subcutaneous myxomas as ill-defined, heterogeneous hypoechoic masses in 1 patient.
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