Key result
Renal artery stenting lowers creatinine ~49% in bilateral renal artery stenosis.
Why the study?
The incidence of bilateral renal artery stenosis due to atherosclerosis is increasing, and rapid progression of renal dysfunction may result from bilateral renal artery stenosis in addition to rapidly progressive glomerulonephritis with crescent formation.
Case Report (n=1)
No
Shows improved blood pressure and renal function after renal angioplasty and stenting in accelerated renovascular hypertension, indicating bilateral renal artery stenosis as an important cause.
A 76-year-old man developed progressive renal dysfunction with refractory hypertension. Bilateral renal artery stenosis due to atherosclerosis was revealed. Both the hypertension and renal dysfunction were improved by percutaneous transluminal renal angioplasty with stenting. Based on the rapidly progressive elevation of plasma renin activity and the improvement of both renal dysfunction and hypertension after stenting, this was considered a case of "accelerated" renovascular hypertension. There have been an increasing number of patients with bilateral renal artery stenosis due to atherosclerosis. The present case reminds us that a rapid progression of renal dysfunction suggests, in addition to besides rapidly progressive glomerulonephritis with crescent formation, bilateral renal artery stenosis, the incidence of which is on the rise. In the present case, angioplasty with stenting was effective for blood pressure control and preservation of renal function.
No takes yet. Share an insight, caveat, or question.
Doi et al. (2002) conducted a case report in Bilateral atherosclerotic renal artery stenosis with accelerated renovascular hypertension and progressive renal dysfunction (n=1). Percutaneous transluminal renal angioplasty (PTRA) with intravascular stenting was evaluated on Serum creatinine and systemic plasma renin activity after PTRA with stenting. Percutaneous transluminal renal angioplasty with stenting reduced serum creatinine from 3.5 to 1.8 mg/dl and plasma renin activity from 10.0 to 1.0 ng/ml/h in bilateral renal artery stenosis.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: