Key result
Female sex was associated with a numerically higher but statistically non-significant rate of GDS-15 depression compared to male sex (86.3% vs 76.6%, p=0.141) among older inpatients with heart failure.
Why the study?
Depression is common among older inpatients with heart failure and may present differently by sex, motivating this comparison of sex differences in GDS-15 components.
Does the prevalence of depression and the distribution of GDS-15 components differ between male and female hospitalized older patients with heart failure?
Cross-Sectional (n=137)
No
Does the prevalence of depression and the distribution of GDS-15 components differ between male and female hospitalized older patients with heart failure?
Answers are grounded in this paper and cite their sources.
Hospitalized older patients with heart failure exhibit a very high prevalence of depression (81.8%), frailty (86.8%), and IADL dependence (85.4%) with no significant sex differences, supporting routine GDS-15 depression screening and comprehensive geriatric assessment for all older heart failure inpatients regardless of sex.
Depression is common among older inpatients with heart failure and may present differently by sex. To describe demographic, comorbidity and geriatric characteristics, and to compare sex differences in components of the 15-item Geriatric Depression Scale (GDS-15) among hospitalised older patients with heart failure at Thong Nhat Hospital. A cross-sectional study of 137 inpatients aged ≥60 years with heart failure at the Department of Cardiology, Thong Nhat Hospital (64 men, 73 women). Categorical variables were presented as frequency and percentage; skewed continuous variables as median and interquartile range. Comparisons between men and women used chi-square/Fisher’s exact or Mann-Whitney tests; depression was defined as GDS-15 ≥5. Median BMI was 22 (IQR 21-24) kg/m². Hypertension, dyslipidaemia and diabetes were the most common comorbidities. IADL dependence occurred in 85.4%, frailty in 86.8%, and GDS-15 depression in 81.8%; median GDS-15 score was 6 (IQR 5-7). No statistically significant sex differences were found in comorbidities, ejection fraction, ADL/IADL dependence, frailty, depression, or any GDS-15 component. The six GDS-15 items with the highest “yes” rates by sex were memory complaints, feeling full of energy, and preferring to stay home. Depression screened by GDS-15 was highly prevalent; women had a numerically higher rate than men without reaching statistical significance. Routine GDS-15 depression screening should be integrated into nursing care regardless of sex.
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Tuyet et al. (2026) conducted a cross-sectional in Heart failure and geriatric depression (n=137). Female sex vs. Male sex was evaluated on Depression defined as 15-item Geriatric Depression Scale (GDS-15) score ≥5 (p=0.141). Female sex was associated with a numerically higher but statistically non-significant rate of GDS-15 depression compared to male sex (86.3% vs 76.6%, p=0.141) among older inpatients with heart failure.
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