Key result
Autologous blood pleurodesis resolves refractory chylothorax within 15 days in Behçet's disease.
Why the study?
Chylothorax is a very rare complication of Behçet's Disease usually associated with thrombosis in the major venous system.
Case Report (n=1)
No
Answers are grounded in this paper and cite their sources.
Should not yet change practice in refractory chylothorax; leaves open the role of autologous blood pleurodesis in Behçet's disease.
Behçet's Disease (BD) is a multisystemic vasculitis which usually affects optical, genital, and oral mucosae and often reoccurs intermittently. Chylothorax is a very rare complication of BD which usually causes thrombosis in the major venous system. A 27-year-old man with a 10-year history of BD referred to our cardiovascular surgery department with symptoms of serious aches in the left arm, edema, and apparent veins on the left anterior chest wall. A total thrombosis of the left internal and external jugular veins and the left subclavian vein was observed. One month after a successful treatment and discharge, the patient returned to our clinic with symptoms of dyspnea and coughs. A chest radiograph showed a consolidated region. A milky liquid was aspirated through thoracocentesis from the left thorax, and its biochemical analysis helped us arrive at a diagnosis of chylothorax. The patient was hospitalized and administered corticosteroids and immunosuppressive therapy with a high-carbohydrate and low-fat dietary regimen for BD. Thereafter, a left thoracic drainage system was established. On the seventh day of hospitalization, due to a progressing cheilosis flow, a pleurodesis process was applied with talcum powder. However, the chylous drainage was continued and 60 mL of venous autologous blood was injected into the left thorax through a drainage tube. The treatment was successful, and the patient was discharged from the hospital uneventfully. At 1 month's follow-up, the chest radiograph was normal.
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Demirdaş et al. (2019) conducted a case report in Chylothorax secondary to Behçet's Disease with venous thrombosis (n=1). Autologous blood pleurodesis following talcum powder pleurodesis and medical therapy (corticosteroids, immunosuppressants, anticoagulants, low-fat diet) was evaluated on Resolution of chylous pleural effusion (chylothorax). Autologous blood pleurodesis completely resolved persistent chylothorax within 15 days in a 27-year-old man with Behçet's disease after talc pleurodesis failed.
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