Answers are grounded in this paper and cite their sources.
Eighty adults in areas of Kenya where malaria is holoendemic received presumptive treatment with atovaquone-proguanil and were followed closely. The time to the first Plasmodium falciparum parasitemia was 32 days. This prolonged prophylaxis period has implications for study design when used in malaria intervention trials and cautiously suggests clinical investigation of potential preexposure prophylaxis of malaria.
No takes yet. Share an insight, caveat, or question.
Polhemus et al. (2008) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: