Key result
Acute cholangitis triggers complete heart block via the cardiobiliary reflex.
Why the study?
Bradyarrhythmias caused by the cardiobiliary reflex are rare and have mainly been reported in acute cholecystitis, motivating emphasis on this reflex as a possible cause of bradyarrhythmia in gallbladder and biliary tract diseases.
Case Report (n=1)
No
This case report highlights the cardiobiliary reflex as a rare potential cause of complete heart block and bradyarrhythmia in patients presenting with acute cholangitis and biliary tract disease.
Answers are grounded in this paper and cite their sources.
May indicate reversible heart block in acute cholangitis; hypothesis-generating and requires confirmation before clinical consideration.
Background: Gallbladder and biliary tract diseases may manifest as cardiac symptoms, ischemic electrocardiographic changes, and arrhythmias. Albeit rare, cases of bradyarrhythmia caused by the cardiobiliary reflex have been reported in the context of acute cholecystitis. The case discussed herein emphasizes the cardiobiliary reflex as a possible cause of bradyarrhythmia in patients with gallbladder and biliary tract diseases.
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Kılıç et al. (2026) conducted a case report in Complete heart block in acute cholangitis (n=1). Cardiobiliary reflex in acute cholangitis was evaluated on Complete heart block. The cardiobiliary reflex caused complete heart block in a patient with acute cholangitis (N=1).
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