Tumor tagging: making cold tumors visible to immunotherapy

Keywords cancer immunotherapy , cold tumors , immune recognition , mRNA vaccines , oncolytic viruses , tumor tagging Citation Wang T-Y, Sun Y, Cong F and Tang Y-D (2026) Tumor tagging: making cold tumors visible to immunotherapy . Front. Immunol. 17:1981961. doi: 10.3389/fimmu.2026.1981961 Received 29 August 2026 Revised 18 September 2026 Accepted 14 October 2026 Published 28 October 2026 Volume 17 - 2026 Edited by Gaurav Sharma , The University of Texas Health Science Center at San Antonio, United States Reviewed by Isaac Quiros Fernandez , University of Costa Rica, Costa Rica Updates Check for updates Copyright © 2026 Wang, Sun, Cong and Tang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. * Correspondence: Yan-Dong Tang, tangyandong@caas.cn ; Feng Cong, Congfeng@zhku.edu.cn †These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.