Association Between Serum Ferritin and Glycemic Control in Patients With Type 2 Diabetes Mellitus

Background: Type 2 diabetes mellitus (T2DM) is associated with disturbances in glucose metabolism and chronic lowgradeinflammation. Serum ferritin, a marker of body iron stores and an acute-phase reactant, may be associated withglycemic control in patients with T2DM. The objective is to assess the association between serum ferritin levels andglycemic control among patients with type 2 diabetes mellitus attending a tertiary care hospital. Materials and Methods: Ahospital-based observational analytical study was planned over six months among 100 patients with T2DM. Demographicand clinical details were collected, and serum ferritin, glycated hemoglobin (HbA1c), and fasting blood glucose levels wereassessed. Participants were categorized into adequate glycemic control (HbA1c <7%) and inadequate glycemic control(HbA1c ≥7%) groups. The association between serum ferritin and glycemic parameters was assessed using correlationanalysis, while biochemical parameters were compared between the two groups. Results: A total of 100 participants wereincluded in the study, with a mean age of 52.6 ± 10.2 years; 56% were males. Inadequate glycemic control (HbA1c ≥7%)was observed in 65% of participants. Mean serum ferritin levels were significantly higher among participants with HbA1c≥7% than among those with HbA1c 100 ng/mL more frequently had inadequate glycemic control than those with ferritin≤100 ng/mL (81.8% vs. 44.4%; p < 0.001). Conclusion: Serum ferritin may be associated with glycemic control in patientswith T2DM and may provide supplementary information when interpreted alongside established glycemic parameters andthe patient's clinical profile.