Association of Serum Ferritin Level and Hba1c Level in Diabetic Individuals

Background: The prevalence of diabetes mellitus, a group of metabolic disorders characterized by high blood sugar levels, is rapidly increasing worldwide. Serum Ferritin is an acute phase reactant, which is a marker of iron stores in the body. Many studies explain that raised body iron stores and subclinical hemochromatosis have been associated with the development of glucose intolerance, metabolic syndrome, and possibly the development of diabetic retinopathy, nephropathy, and vascular dysfunction. Glycemic control is closely associated with cardiovascular complications in diabetes. Changes in serum ferritin levels are associated with glucose intolerance. This study was conducted to know about the association between Serum Ferritin and HbA1C in Diabetic women and to study whether a correlation between S. ferritin and FBS, HbA1c exists. The purpose of the study was to evaluate the Serum ferritin level and glycemi Objectives: c index in diabetic women and to investigate the relationship between in controls and diabetic women as well as between insulin, Serum ferritin, and glycated hemoglobin. In this study, 100 subjects were studied, and a case-control stu Materials and Methods: dy was done with 50 outpatients and inpatients with diagnosed cases of Diabetes mellitus and 50 healthy individuals as controls from the Department of Medicine, S. N. Medical College, Agra. Serum levels of, ferritin, and blood glucose levels were measured by Chemiluminescence, and blood glycated hemoglobin (HbA1c) was measured by the HPLC method. The statistical analysis was carried out using the student's t-test. There was a positive correlation b Results: etween serum ferritin and HbA1c. This study found that high levels of ferritin can predict future cardiovascular Discussion & Conclusion: complications in individuals with diabetes. This study investigated its relationship with clinical and laboratory parameters of diabetes mellitus. It is observed that serum ferritin level is higher in participants with prediabetes with increments of HbA1c (%).