Lesion Sterilization and Tissue Repair (LSTR) in Primary Teeth: A Narrative Review

Lesion sterilization and tissue repair (LSTR) is a minimally invasive endodontic technique that can help eliminate infection and promote natural healing in the dental and periapical tissues.This technique is based on the premise that polymicrobial root canal infections require broad-spectrum antimicrobial control, which is particularly important in primary teeth and anatomically challenging cases where traditional root canal instrumentation may be inadequate.The biological basis, evolution, antimicrobial agents, clinical procedures, outcomes, limitations, controversies, and future directions of LSTR are discussed.Current evidence suggests that LSTR may achieve good clinical and radiographic success in selected cases.However, antibiotic resistance, tooth discoloration, variations in protocols, and a lack of long-term data remain pertinent concerns.LSTR is a treatment option in pediatric endodontics; however, further studies are needed to standardize the protocol and establish its long-term benefits and safety.