Key result
Primary PCI successfully treats wasp sting-induced Type II Kounis syndrome presenting with total LAD occlusion.
Why the study?
Kounis syndrome is a rare but serious condition defined by acute coronary syndrome occurring alongside a hypersensitivity reaction, presenting diagnostic and treatment challenges.
Case Report (n=1)
No
This case report highlights the diagnostic and therapeutic challenges of Type II Kounis syndrome presenting as acute anterior STEMI with total proximal LAD occlusion following a bee sting, successfully managed with primary PCI.
Supports considering Kounis syndrome in sting-associated STEMI; leaves open need for prospective validation of tailored management.
Kounis syndrome (KS), also known as allergic angina, is a rare but serious condition defined by acute coronary syndrome occurring alongside a hypersensitivity reaction. We report the case of a 42‐year‐old male smoker who developed Type II KS after a hymenoptera sting. The patient came to the emergency department with a sudden decreased level of consciousness and retrosternal chest pain. Electrocardiography showed ST‐segment elevation in the anterior leads, and coronary angiography revealed total proximal left anterior descending artery occlusion. Primary percutaneous coronary intervention (PCI) was performed successfully. Echocardiography documented a left ventricular ejection fraction (LVEF) of 35% with regional wall motion abnormalities, indicating significant myocardial injury. The patient was discharged with a treatment plan that included valsartan, spironolactone, bisoprolol, ticagrelor, acetylsalicylic acid, and atorvastatin. This case highlights the diagnostic and treatment challenges of KS and stresses the need for early recognition and a team‐based approach to achieve better clinical results.
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Tarkiani et al. (2026) conducted a case report in Type II Kounis syndrome (acute anterior ST-elevation myocardial infarction following hymenoptera sting) (n=1). Hymenoptera (bee) sting was evaluated on Clinical resolution and left ventricular ejection fraction following primary percutaneous coronary intervention. Hymenoptera sting triggered Type II Kounis syndrome with total proximal LAD occlusion and LVEF of 35% in a 42-year-old male smoker, successfully treated with primary PCI.
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