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Microalgal attached cultivation circumvents gas-liquid separation issues of liquid-suspended cultivation, yet performance under reduced gravity remains unevaluated. As a proof-of-concept, we evaluated Arthrospira platensis ( Spirulina ) cultivation under artificial 1G, 1/6G, and microgravity (µG) on the International Space Station. Spirulina expanded without cell detachment, medium floating, or component separation, with relative radial growth rates of 0.28% 0.5 day −1 (1G), 0.22% 0.5 day −1 (1/6G), and 0.17–0.21% 0.5 day −1 (µG), demonstrating feasibility in space.
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Inada et al. (2026) studied this question.
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