Key result
Bilateral cardiac sympathetic denervation achieves complete response in ~67% of refractory electrical storm cases.
Why the study?
The sympathetic nervous system plays an important role in ventricular arrhythmogenesis, and while left cardiac sympathetic denervation decreases the incidence of ventricular arrhythmias and sudden cardiac death, bilateral cardiac sympathetic denervation was evaluated for the management of electrical storm.
Does bilateral cardiac sympathetic denervation reduce persistent ventricular arrhythmias and defibrillator shocks in patients with refractory electrical storm?
Cohort (n=6)
Does bilateral cardiac sympathetic denervation reduce persistent ventricular arrhythmias and defibrillator shocks in patients with refractory electrical storm?
Bilateral cardiac sympathetic denervation appears feasible and beneficial for the acute suppression of refractory electrical storm in patients who have failed maximal medical therapy and catheter ablation.
To the Editor: The sympathetic nervous system plays an important role in ventricular arrhythmogenesis. Left cardiac sympathetic denervation (LCSD) decreases the incidence of ventricular arrhythmias (VAs) and sudden cardiac death in patients with severe VAs ([1,2][1]). However, when LCSD is
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Ajijola et al. (2011) conducted a cohort in Electrical storm characterized by incessant ventricular tachycardia or repeated episodes of ventricular fibrillation (n=6). Bilateral cardiac sympathetic denervation (BCSD) or adjunctive right cardiac sympathetic denervation (RCSD) after prior LCSD was evaluated on Complete response (suppression of persistent ventricular arrhythmias). Bilateral cardiac sympathetic denervation achieved a complete response in 66.7% (4/6) and partial response in 16.7% (1/6) of patients with refractory electrical storm.
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