Surviving despite accumulating toxic metabolites inside the cell is a defining feature of cancer evolution. In the current issue of Cell Reports , Eric Cheung and coworkers identify a mechanism that enables the survival of malignant pancreatic ductal adenocarcinoma (PDAC) cells through the sequestration of reactive iron. 1 1. Cheung, E. ∙ Wu, M.-H. ∙ Cheng, W.-C. ... Macrophage-Induced Ferritin Expression Protects Pancreatic Cancer Cells from Ferroptosis Cell Rep. 2026; 45 Full Text Full Text (PDF)
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