Mpox (monkey pox) is a zoonotic disease caused by the orthopox virus. Since May 2022, Mpox cases have increased sharply in various countries including Indonesia. Good knowledge is expected to form a positive attitude in facing the threat of this disease. To determine the relationship between knowledge and attitude of health cadres regarding Mpox disease in Cirebon City. This study used a cross-sectional design with an observational analytic approach. Data collection was conducted in May-June 2025 at 5 health centers in Cirebon City. Respondents consisted of 100 health cadres selected through cluster random sampling. Data were collected using a structured questionnaire and analyzed with the Spearman test. The results showed that 53% of cadres had low knowledge, 30% moderate knowledge, and 17% high knowledge. A total of 69% of respondents had a negative attitude towards Mpox prevention, while 31% had a positive attitude. There was a significant and strong relationship between knowledge and attitude of health cadres (p0.001; rho=0.773). Most health cadres in Cirebon City have low knowledge and negative attitudes towards Mpox prevention. There is a strong and significant relationship between knowledge level and attitude. Capacity building of cadres through training and health education is needed to support Mpox prevention efforts. Keywords: Mpox, Knowledge, Attitude, Health Cadres, Cirebon. ABSTRAK Mpox (cacar monyet) adalah penyakit zoonosis yang disebabkan oleh virus orthopox. Sejak Mei 2022, kasus Mpox meningkat tajam di berbagai negara termasuk Indonesia. Pengetahuan yang baik diharapkan dapat membentuk sikap positif dalam menghadapi ancaman penyakit ini. Mengetahui hubungan antara pengetahuan dengan sikap kader kesehatan mengenai penyakit Mpox di Kota Cirebon. Penelitian ini menggunakan desain cross-sectional dengan pendekatan analitik observasional. Pengambilan data dilakukan pada Mei-Juni 2025 di 5 Puskesmas di Kota Cirebon. Responden terdiri dari 100 kader kesehatan yang dipilih melalui cluster random sampling. Data dikumpulkan menggunakan kuesioner terstruktur dan dianalisis dengan uji Spearman. Hasil penelitian menunjukkan 53% kader memiliki pengetahuan rendah, 30% pengetahuan sedang, dan 17% pengetahuan tinggi. Sebanyak 69% responden memiliki sikap negatif terhadap pencegahan Mpox, sementara 31% memiliki sikap positif. Terdapat hubungan yang signifikan dan kuat antara pengetahuan dengan sikap kader kesehatan (p0,001; rho=0,773). Sebagian besar kader kesehatan di Kota Cirebon memiliki pengetahuan yang rendah dan sikap negatif terhadap pencegahan Mpox. Terdapat hubungan yang kuat dan signifikan antara tingkat pengetahuan dengan sikap. Peningkatan kapasitas kader melalui pelatihan dan edukasi kesehatan sangat diperlukan untuk mendukung upaya pencegahan Mpox. Kata Kunci: Mpox, Pengetahuan, Sikap, Kader Kesehatan, Cirebon.
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Ayu et al. (2026) studied this question.
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