Prostate cancer metastasis to the stomach wall: a case report and literature review

Prostate cancer (PCa) ranks first in cancer morbidity among the male population of Russia and third in cancer-related mortality among men. The presence of metastatic disease significantly worsens prognosis. PCa most frequently metastasizes to bone and regional lymph nodes. Gastric wall involvement in combination with peritoneal carcinomatosis is extremely rare, partly due to the limited sensitivity of conventional diagnostic modalities in patients with PCa. We present the first case in the Russian literature of asymptomatic gastric wall metastasis from PCa with concurrent peritoneal carcinomatosis, diagnosed 15 years after the initial diagnosis. A notable feature of this case is the absence of bone or lymph node metastases, which are the typical sites of dissemination, suggesting the potential for secondary lesions to occur in unusual locations. The metastatic lesion and carcinomatosis were identified by using positron emission tomography combined with computed tomography with prostate-specific membrane antigen and subsequently confirmed histologically. This case illustrates the importance of high-tech diagnostic methods for the detection of atypical metastases.