Knee osteoarthritis (OA) is the most common form of osteoarthritis worldwide and a leading cause of chronic pain and disability in older adults. Adults aged 60 to 70 years carry a high burden of symptomatic disease and frequently have comorbidities that limit the long-term use of oral analgesics and nonsteroidal anti-inflammatory drugs, which has stimulated interest in non-pharmacological physical agents. High-intensity electromagnetic stimulation devices, such as the Super Inductive System (SIS; BTL Industries), generate rapidly changing magnetic fields of up to 3 tesla that induce electric currents capable of depolarizing peripheral nerves and eliciting muscle contractions without skin contact. These devices are increasingly used in rehabilitation settings for knee pain, yet their clinical evidence has not been critically summarized. This narrative review describes the physical principles and proposed analgesic mechanisms of electromagnetic therapies, distinguishes high-intensity repetitive peripheral magnetic stimulation (rPMS) from low-intensity pulsed electromagnetic field (PEMF) therapy, and synthesizes the available clinical evidence with emphasis on adults aged 60 to 70 years. As of October 2026, no peer-reviewed randomized controlled trial had evaluated the SIS specifically in knee OA, and no trial had restricted enrollment to the 60- to 70-year age range. Evidence for the SIS is limited to uncontrolled pilot studies in mixed musculoskeletal pain. A small sham-controlled trial of single-session rPMS in knee OA, with a mean participant age of 63 years, found no significant short-term difference in pain intensity. Low-intensity PEMF has a larger evidence base, including a Cochrane review that reported a moderate reduction in pain and randomized trials in older adults, but these findings cannot be directly extrapolated to high-intensity devices. High-intensity electromagnetic stimulation is therefore a biologically plausible but unproven adjunct for knee OA pain. Well-designed, sham-controlled trials with standardized stimulation parameters, adequate follow-up, and age-specific analyses are needed before it can be recommended in routine care.
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Noe Ivan Luna Jaramillo (2026) studied this question.
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