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The petai cina plant (Leucaena leucocephala) is a legume plant and has been used in traditional medicine in the community. This study aims to determine the antibacterial and antifungal activity of the ethanol extract of petai cina fruit peel in inhibiting the growth of Salmonella gastroenteritis bacteria, Methicillin Resistant Staphylococcus aureus (MRSA) and Aspergillus flavus fungi. The method used in this study was phytochemical screening of the extract and antimicrobial testing by disc diffusion method using test concentrations of 20%; 10%; 5%; and 2.5% with chloramphenicol as a positive control and DMSO as a negative control. The results of the phytochemical screening test on the ethanol extract of petai cina fruit peel contained compounds containing alkaloids, saponins, phenolics, flavonoids, steroids, and triterpenoids. The results of antibacterial testing against Salmonella gastroenteritis showed that the ethanol extract of petai cina fruit peel had an inhibition zone diameter of 15.35 mm (20%) with a strong category, against MRSA the inhibition zone diameter was 9.51 mm (20%) with a moderate category and antifungal testing against Aspergillus flavus the inhibition zone diameter was 17.33 mm (20%) with a strong category. The conclusion of this study is that the ethanol extract of petai cina fruit peel has antibacterial and antifungal activity.
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Faroliu et al. (2026) studied this question.
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