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One of the most common chronic illnesses is diabetes, which requires ongoing observation,individualized care, and quick action to avoid complications. The real-time monitoring ofphysiological indicators has advanced thanks to recent advancements in Internet of Things(IoT) technology, including wearable sensors, smart insulin pumps, continuous glucosemonitoring devices, and mobile healthcare apps. Large language models (LLMs) are now apotent tool in the artificial intelligence toolkit for decision support, clinical reasoning, naturallanguage comprehension, and healthcare communication. Thanks to the power of both IoTand LLMs, there are plenty of possibilities for smart diabetes care, and much of the data fromsensors can now be used to inform healthcare insights. The authors have conducted aliterature review on the topic of diabetes monitoring systems with IoT technologies, as wellas machine learning in predicting glucose levels and the growing role of LLMs in healthcare.The goal of this paper is to provide a summary of the state of the art in machine learningmethods for glucose prediction, IoT-based diabetes monitoring systems, and the expandingrole of LLMs in healthcare. The most recent developments in diabetic treatment using LLMare covered in this article, including patient interaction platforms, clinical summaryautomation, conversational healthcare assistants, and tailored recommendation systems. Anexamination of existing research is done to identify trends, strengths and weaknesses. Inaddition, issues concerning with privacy, security, explain ability, model reliability andethical aspects are discussed. The research gaps are identified, and the future directions areproposed so that motivating intelligent, scalable and patient-centric diabetes managementsystems are developed. Overall, the findings indicate that the potential for IoT and LLM towork together in healthcare is enormous, with the ability to improve treatment adherence,proactive management of diseases, and better healthcare outcomes.
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Sharma et al. (2026) studied this question.
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