Key result
Higher daily energy expenditure is linked to lower serum apo A-II, C-II, C-III, and E levels.
Why the study?
This study examined the relationships among serum apolipoproteins, physical variations, nutrition, and energy expenditure.
Cross-Sectional (n=169)
No
Answers are grounded in this paper and cite their sources.
May inform lifestyle effects on apolipoproteins in men; leaves open causal impact on lipid metabolism.
The relationships among the apolipoproteins (apo), physical variations, nutrition and energy expenditure were studied by using 169 healthy men who had been randomly selected from among 1, 084 male participants in 1989 in Tanushimaru, Kyushu, Japan.The results of the univariate analysis showed that the concentration of apo A-I was positively related to the percentage of calories from alcohol (alcohol (%)), and that the concentration of apo A-II was positively related to obesity and alcohol (%), and negatively related to age and energy expenditure, while, the concentration of apo B was positively related to obesity. Concerning apo C-II, C-III and E, significant relations to energy expenditure and obesity were observed.Multiple linear regression analysis was performed to exclude those factors which had been overestimated by the univariate analysis. Significant correlations between apo A-I and obesity, alcohol (%), smoking and daily cholesterol intake were observed. The concentration of apo A-II was well indicated by age, obesity, energy expenditure, alcohol (%) and smoking. The concentration of apo B was correlated only with obesity, while the apo B/A-I ratio showed a correlation with both obesity and alcohol consumption. Apo C-II, C-III and E were well indicated by daily energy expenditure.Therefore, it is safe to conclude that the metabolism of serum apolipoproteins is influenced by various environmental factors. Further detailed studies on these factors are required to help prevent atherosclerotic diseases through the modification of lifestyles.
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Adachi et al. (1992) conducted a cross-sectional in Serum apolipoprotein metabolism in healthy community-dwelling men (n=169). Daily energy expenditure and environmental factors (obesity, alcohol intake, smoking, nutrition) vs. Low energy expenditure (<44.5 kcal/kg/day) and varying lifestyle levels was evaluated on Serum apolipoprotein concentrations (A-I, A-II, B, C-II, C-III, E) (p=<0.01). Higher daily energy expenditure was independently and negatively correlated with serum apo A-II (p<0.05), apo C-II (p<0.001), apo C-III (p<0.05), and apo E (p<0.01) in healthy Japanese men.
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