Key result
Multivessel CAD linked to ~11-point higher persistent grade II-III diastolic dysfunction at 1 year post-PCI.
Why the study?
The natural development and prognostic value of left ventricular diastolic dysfunction in patients with acute non-Q-wave myocardial infarction after percutaneous intervention needed to be more precisely characterized.
Does multivessel coronary affection compared to single-vessel affection result in worse or more persistent left ventricular diastolic dysfunction at 1 year in patients with non-Q-wave myocardial infarction after infarct-related artery percutaneous intervention?
Cohort (n=95)
Does multivessel coronary affection compared to single-vessel affection result in worse or more persistent left ventricular diastolic dysfunction at 1 year in patients with non-Q-wave myocardial infarction after infarct-related artery percutaneous intervention?
In patients with non-Q-wave MI undergoing infarct-related artery PCI, those with multivessel coronary disease experience more severe and persistent left ventricular diastolic dysfunction over 1 year compared to those with single-vessel disease.
Answers are grounded in this paper and cite their sources.
May warrant closer diastolic surveillance in multivessel non-Q-wave MI; leaves open whether complete revascularization improves recovery.
Aim: To make natural development more exact to state the value of scientific prognostication of dia- stolic dysfunction with acute myocardial infarction without Q-wave after percutaneous intervention.materials and methods: 95 patients were subjected to coronography and revascularization of in- farct-related artery. The patients were divided into 2 groups depending on angiographic results with single and multivessel affection. during first 48 hours from the beginning of the disease they were under ECHO examination.Results: Left ventricle affections dF data were revealed relatively to heaviness of affection in cor- onary vessels without reliable differences in local and global contractility. Primordialy the 1 group contained 14 (54%) patients of I grade dd, 5 (19%) with II grade, 1 (8%) with III grade, 6 (19%) without dd. A year later: 18 (70%) with I grade dd, 3 (12%) with II, patients with III grade were not redictered, 5 (18%) without dd. In group 2 within first 48 hours 37 (54%) patients had I grade,25 (36%) II grade, 7 (10%) III grade. In a year there were 46 (67%) with I grade, 13 (19%) II grade, 3 (4%) with III grade dd, 7 (10%) without dd.Conclusions: Obtained data indicate of a higher sensitivity dependently dF ischemia.In contrast to myocardial infarction group with coronary bloodstream fully restored within short terms, in group with multivessel affections a more heavy dd data preserved longer, in spite of infarct related artery revascularization. Also unfavourable events were revealed.
No takes yet. Share an insight, caveat, or question.
Khomyakova et al. (2017) conducted a cohort in Acute non-Q-wave myocardial infarction after percutaneous intervention (n=95). Multivessel coronary affection vs. Single-vessel coronary affection was evaluated on Left ventricular diastolic dysfunction (grades I, II, III, or none) at 1 year. Multivessel vs single-vessel disease in non-Q-wave MI post-PCI showed more persistent grade II-III diastolic dysfunction at 1 year (23% vs 12%) despite infarct-related artery revascularization.
Synapse has enriched 10 related papers. Consider them for comparative context: