The imaging techniques in multiple myeloma

MM is a B-cell lymphoproliferative disorder whose morphological substrate is plasma cells. One of the characteristic clinical manifestations of the disease is skeletal involvement, which is included in the diagnostic criteria of the CRAB acronym. Various widely adopted radiological and combined methods are used for diagnosis, staging, and assessment of the depth of response to therapy.This article discusses current approaches to imaging skeletal involvement and extramedullary manifestations of multiple myeloma, the diagnostic capabilities and features of application of radiological methods in clinical practice.