Pyogenic Granuloma Arising from a Port-Wine Stain on the Scalp: A Case Report and Literature Review

Pyogenic granulomas (PGs), also known as lobular capillary hemangiomas, are common reactive lesions that are non-neoplastic in nature. While they typically present as isolated lesions, they can rarely develop from preexisting port-wine stains (PWSs). PWS-associated PGs may occur spontaneously but are often linked to pregnancy or prior treatments such as laser therapy, intense pulsed light therapy, or radiotherapy. Here, we report a rare case of a PG arising from a PWS on the parietal scalp of a 27-year-old man with no history of trauma or prior treatment for his PWS. Given the potential for secondary lesion development in PWS, regular monitoring is essential, particularly in patients with associated risk factors.