Ischemic stroke and cardiovascular comorbidity

This review presents data on the prevalence and comorbidities of cardiovascular diseases (CVDs), which are risk factors for the development of acute cerebrovascular accident (ACVA) or myocardial infarction (MI) and the risk of adverse outcomes. CVDs have various markers of cerebral damage, it’s manifested by cognitive decline and down to the development of dementia. The primary pathogenetic mechanism for the development of stroke-associated cardiovascular disease is decreasing cerebral blood flow and microcirculatory network density, i.e. the development of cerebrovascular insufficiency. Most patients with cerebral lesions following stroke have concomitant cardiac pathology, which impacts the post-stroke period and patient survival. In turn, stroke causes cardiac complications and/or the development of newly diagnosed cardiovascular diseases due to impaired autonomic regulation of the cardiovascular system and hemodynamic mechanisms.