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Introduction. Cell free DNA (cfDNA), being an easily accessible and promising clinical material, as previously shown in obstetrics and general oncology, is of particular interest in hematology. In recent years, the study of plasma cfDNA in hematological diseases has been gaining increasing interest among researchers and physicians. To date, a signifi cant amount of data cfDNA and tumor cfDNA (cftDNA) in patients with diseases of the blood system has been accumulated in the world literature. Aim: to study the literature data on the cfDNA in aggressive B-cell lymphomas and Hodgkin’s lymphoma (HL). Main fi ndings. The review presents the literature data on the study of cfDNA, the possibilities and limitations of using various methods of studying cfDNA in patients with aggressive B-cell lymphomas and HL.
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Smirnova et al. (2025) studied this question.
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