Primary osteogenic sarcoma of pulmonary artery.

Q: What is the clinical evidence from this study?

Study design: Case Report. Population: Primary osteogenic sarcoma of the pulmonary artery (n=1). Intervention: Thoracotomy with right pneumonectomy and left atrium resection. Primary outcome: Tumor recurrence and survival.

Q: What does this research mean for the field?

Primary osteogenic sarcoma of the pulmonary artery carries a poor prognosis characterized by rapid local recurrence and mortality even after radical surgical resection with clear margins. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Isao Kimura; 英則 木内; Yoshio Sakamoto; Keiichiro Yamamoto; Yutaka Dohi; Motohide Takahama

doi:10.2169/internalmedicine1962.29.32

January 1, 1990Japanese Journal of MedicineOpen Access

Primary osteogenic sarcoma of pulmonary artery.

View Full Paper

Ask AI

Bookmark

Share

Key Points

To describe the presentation, diagnosis, and surgical outcome of a rare primary osteogenic sarcoma arising directly from the pulmonary artery.
Diagnostic workup in a 44-year-old female included chest radiography, computed tomography, bronchofiberscopy, and radionuclide scintigraphy.
Surgical intervention consisting of exploratory thoracotomy, right pneumonectomy, and partial resection of the left atrium followed by histopathological examination.
Pathological examination of the resected 12 x 8 x 6.5 cm specimen confirmed primary osteogenic sarcoma of the pulmonary artery obstructing the right main stem bronchus.
Comprehensive clinical and radiological evaluations confirmed no evidence of primary osteogenic sarcoma in the skeletal system or other extrathoracic organs.
Recurrence was identified in the left atrial remnant four months postoperatively, progressing to superior vena cava syndrome and death from respiratory insufficiency.

Study Design

Type

Case Report (n=1)

Multicenter

No

PICO

P

Population

1 44-year-old woman in Japan with primary osteogenic sarcoma of the right pulmonary artery, initially misdiagnosed as hilar lymph node tuberculosis, followed for 2 years until death.

I

Intervention / Comparator

Thoracotomy with right pneumonectomy and left atrium resection

O

Primary Outcome

Tumor recurrence and survival

Limitations

Single patient case report
Initial misdiagnosis as hilar lymph node tuberculosis delayed surgical resection by over 1 year
No autopsy was performed after death

Ask about this paper

Answers are grounded in this paper and cite their sources.

Implication

Rapid recurrence despite clear margins signals aggressive biology; leaves open need for effective systemic therapies in pulmonary artery sarcoma.

Abstract

A 44-year-old woman was hospitalized for nonproductive cough. Chest roentogenogram revealed a calcified nodular mass at the right hilum. The patient was treated as tuberculosis of the hilar lymph node, however, her symptoms exacerbated within a year. A tumor obstructing the right main stem bronchus was demonstrated on bronchofiberscopic examination. Thoracotomy was carried out and tumor was diagnosed as primary osteogenic sarcoma of the pulmonary artery by pathological examination of the resected specimen. There was no clinical finding of osteogenic sarcoma throughout the bones.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Kimura et al. (1990) conducted a case report in Primary osteogenic sarcoma of the pulmonary artery (n=1). Thoracotomy with right pneumonectomy and left atrium resection was evaluated on Tumor recurrence and survival.

synapsesocial.com/papers/6aed311a8b78d4bc19113b03 https://doi.org/10.2169/internalmedicine1962.29.32

View Full Paper

Ask AI

Bookmark

Share

Primary osteogenic sarcoma of pulmonary artery.

Key Points

Study Design

PICO

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Primary osteogenic sarcoma of pulmonary artery.

Key Points

Study Design

PICO

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading