Why the study?
Residual congestion on handheld ultrasound may be associated with increased readmission and death after ADHF hospitalization, but effective application requires routine use by nonexperts. This study evaluated the ability of HF nurses to deliver a predischarge lung and IVC assessment (LUICA) to predict 90-day outcomes.
Does a nurse-delivered predischarge lung and inferior vena cava ultrasound assessment (LUICA) predict 90-day heart failure readmission or mortality in patients hospitalized with acute decompensated heart failure?
Observational (n=240)
Blinded image review by independent nurses
Yes
Does a nurse-delivered predischarge lung and inferior vena cava ultrasound assessment (LUICA) predict 90-day heart failure readmission or mortality in patients hospitalized with acute decompensated heart failure?
Answers are grounded in this paper and cite their sources.
Heart failure nurses can effectively perform predischarge lung and IVC ultrasound assessments to identify residual congestion that strongly predicts 90-day readmission and mortality in patients with acute decompensated heart failure.
BACKGROUND Residual congestion detected using handheld ultrasound may be associated with increased risk of readmission and death after hospitalization for acute decompensated heart failure (ADHF). However, effective application necessitates routine use by nonexperts delivering clinical care. OBJECTIVES The objective of this study was to determine the ability of heart failure (HF) nurses to deliver a predischarge lung and inferior vena cava (IVC) assessment (LUICA) to predict 90-day outcomes. METHODS In this multisite, prospective, observational study, HF nurses scanned 240 patients with ADHF (median age: 77 years; 56% men) using a 9-zone LUICA protocol. Obtained images were reviewed by independent nurses who were blinded to clinical characteristics and outcomes. Based on a B-line cut-off of 10, patients were dichotomized as congested (n = 115) or not congested (n = 125). RESULTS Congested patients were more likely to have previous cardiac operations, long-standing HF (>6 months), and renal impairment. At 90 days, HF readmission or mortality occurred in 42 congested patients (37%) compared with 18 noncongested patients (14%). Pulmonary congestion increased at 30-day (OR: 3.86; 95% CI: 1.65-8.99; P < 0.01) and 90-day (OR: 3.42; 95% CI: 1.82-6.4; P < 0.01) HF readmission or mortality risk and 90-day mortality (OR: 5.18; 95% CI: 1.44-18.69; P < 0.01). Pulmonary congestion increased the 90-day odds of HF readmission and/or death by 3.3- to 4.2-fold (P < 0.01), independent of demographics, HF characteristics, comorbidities, and event risk score. Over 90 days, days alive out of hospital were fewer (78.3 ± 21.4 days vs 85.5 ± 12.4 days; P < 0.01) in congested patients. CONCLUSIONS LUICA can be a powerful tool for detection of predischarge residual congestion. HF nurses can obtain images and provide diagnostic reports that are predictive of ADHF outcomes.
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Zisis et al. (2022) conducted an observational in Acute decompensated heart failure (n=240). Predischarge pulmonary congestion (>=10 B-lines on 9-zone nurse-provided LUICA protocol) vs. Not congested (<10 B-lines) was evaluated on 90-day heart failure readmission or mortality (OR 3.42, 95% CI 1.82-6.4, p=<0.01).
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