A comparative study of operative & postoperative parameters in coronary artery bypass grafting patients: Insights from a tertiary care experience

Background: Coronary artery bypass grafting (CABG) remains the standard surgical treatment for multivessel coronary artery disease.Off-pump and on-pump techniques differ in intraoperative management and postoperative outcomes.This study aimed to compare operative and postoperative parameters between off-pump and on-pump CABG patients.Methods: This comparative cross-sectional study was conducted in a cardiac surgery department.A total of 60 patients undergoing CABG were divided into two groups: off-pump CABG (n=30) and on-pump CABG (n=30).Baseline characteristics, operative variables, postoperative clinical outcomes and myocardial injury markers including CK-MB and cardiac troponin I (cTnI) were analyzed.Statistical comparisons were performed using appropriate tests, with p≤0.05 considered significant.Results: Baseline demographic characteristics, risk factors and preoperative cardiac function were comparable between groups.Operative time was significantly shorter in the off-pump group compared to the on-pump group (254.00 ± 28.75 vs. 334.50± 23.72 minutes; p<0.001).Postoperative inotropic support requirement was significantly higher in the on-pump group (76.7% vs. 10.0%;p<0.00001).CK-MB and cTnI levels were significantly elevated in the on-pump group at 6, 12 and 24 hours postoperatively, indicating greater myocardial injury.However, mechanical ventilation time, blood loss, transfusion requirement and postoperative complications showed no significant differences between groups.Conclusion: Both on-pump and off-pump CABG are safe and effective techniques with comparable early clinical outcomes.Off-pump CABG is associated with shorter operative time and reduced perioperative myocardial injury, while on-pump CABG requires greater postoperative inotropic support.