Key result
Off-pump r-MIDCAB with in situ RIMA-to-RCA graft demonstrates patency at 5 months.
Why the study?
Minimally invasive direct coronary artery bypass is usually performed through a left-sided approach, while right-sided MIDCAB using an in situ RIMA-to-RCA graft may offer an alternative surgical option in carefully selected patients with isolated RCA disease unsuitable for PCI.
Is off-pump right-sided minimally invasive direct coronary artery bypass using an in situ RIMA-to-RCA graft technically feasible and patent at 5 months in a patient with isolated RCA disease unsuitable for PCI?
Case Report (n=1)
No
Is off-pump right-sided minimally invasive direct coronary artery bypass using an in situ RIMA-to-RCA graft technically feasible and patent at 5 months in a patient with isolated RCA disease unsuitable for PCI?
Demonstrates the technical feasibility and short-term 5-month patency of off-pump right-sided MIDCAB using an in situ RIMA-to-RCA graft for isolated complex RCA disease unsuitable for PCI.
Answers are grounded in this paper and cite their sources.
May support off-pump r-MIDCAB as an option for PCI-ineligible RCA disease; leaves open confirmation of durability and generalizability in larger studies.
BACKGROUND: Minimally Invasive Direct Coronary Artery Bypass (MIDCAB) is usually performed through a left-sided approach; however, in carefully selected patients, right-sided MIDCAB (r-MIDCAB) may provide an alternative surgical approach for isolated right coronary artery disease. In this case, the Right Internal Mammary Artery (RIMA) was used as an in situ graft to the Right Coronary Artery (RCA). CASE PRESENTATION: We report a 65-year-old man with a history of inferior myocardial infarction treated with two RCA stents in 2015. Recurrent anginal symptoms developed in 2024 despite medical therapy. Coronary angiography demonstrated a severely calcified, tortuous subocclusive RCA lesion immediately distal to the previously stented segment. Repeat PCI was unsuccessful because the lesion could not be crossed. Following multidisciplinary Heart Team evaluation, off-pump r-MIDCAB was performed through a right mini-thoracotomy using an in situ RIMA-to-RCA graft. Transit-Time Flow Measurement (TTFM) showed a mean graft flow of 25 mL/min, pulsatility index of 1.6, diastolic filling of 54%, and backflow of 0.1%. At five-month follow-up, CT coronary angiography demonstrated a patent graft with good distal runoff. CONCLUSION: This case demonstrates the technical feasibility of RIMA-to-RCA revascularization via a right mini-thoracotomy in a carefully selected patient with isolated RCA disease that is unsuitable for PCI. The short-term clinical and imaging findings were favorable; however, a single case with five months of follow-up cannot establish safety, effectiveness, or long-term graft durability. Larger studies with longer follow-up are required.
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Grujic et al. (2026) conducted a case report in Severely calcified, tortuous subocclusive right coronary artery lesion (n=1). Off-pump right-sided minimally invasive direct coronary artery bypass (r-MIDCAB) using an in situ right internal mammary artery (RIMA) to RCA graft was evaluated on Graft patency on CT coronary angiography at 5 months and intraoperative transit-time flow measurement. Off-pump r-MIDCAB with an in situ RIMA-to-RCA graft achieved a mean graft flow of 25 mL/min and remained patent on CT angiography at 5 months.
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