Key result
Infective endocarditis carries persistent ~40% 1-year mortality, with prosthetic valves involved in nearly one-third.
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High mortality persists in prosthetic valve endocarditis; leaves open the need for targeted prevention trials before changing practice.
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I Todorov (2026) conducted an editorial in Infective endocarditis. Infective endocarditis continues to carry a 15-20% in-hospital mortality and up to 40% one-year mortality, with prosthetic valve endocarditis now accounting for 20-30% of all cases.
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