A Review on Climatic Change and Medicine Stability

The stability ofmedicinal dosage preparation a critical component in testingdrug security, effectiveness, characteristics throughout the products shelf life. The issue is especially common in specific areawith increased temperature, relative humidity accelerate physical, chemical and microbiological degradation processes. Shelf life prediction essential consideration during development of pharmaceutical products in all dosage forms. Therefore, throughout pharmaceutical formulation, packaging, stability testing, storage and distribution, climatic zone is a key factor for impact on stability of drugs.The goal of this studies for determining the relationship between changing weather and medications stabilityincluding change in temperature,relativehumidity along with additional environmental conditions. Solubility, drug potency, appearance, effectiveness, moisture content that all may impacted by climatic change which could harm therapeutic efficacy. Standardized conditions and methodsforcarryingoutstabilitytestsareprovidedbyICHandotherregulatoryguidelines.Inaddition to facilitating regulatory approval and global pharmaceutical products harmonization, proper use of ICH stability criteria encourages consistent product quality. Overall, climate change can affect reliability, shelf life of medicine.