RNA-Seq profiling of pancreatic tissues from Sham, AP, and AGK2-treated AP rat models

This dataset contains RNA-Seq transcriptome sequencing data derived from pancreatic tissues of rat models under different experimental conditions. Three groups were included: (1) Sham group (control), (2) acute pancreatitis (AP) group, and (3) AGK2+AP group (AP rats treated with AGK2, a selective SIRT2 inhibitor). The study aims to investigate transcriptomic alterations associated with acute pancreatitis and to evaluate the modulatory effects of SIRT2 inhibition on pancreatic injury and inflammation. These data provide valuable resources for understanding the molecular mechanisms underlying AP progression and the potential therapeutic role of AGK2.