Key result
Valve replacement for carcinoid heart disease carries ~38% mortality but restores NYHA class I in survivors.
Why the study?
Carcinoid heart disease is a rare acquired valvular condition where cardiac surgery is the only definitive symptom-relieving option, prompting an evaluation of postoperative outcomes following heart valve replacement.
Observational (n=8)
No
Answers are grounded in this paper and cite their sources.
Retrospective carcinoid valve surgery outcomes leave open optimal timing and selection; prospective studies needed before practice change.
Background and aim Carcinoid heart disease is a rare, acquired heart valvular disease affecting mainly the right chambers. Cardiac surgery is the only definite symptom relieving option and has significantly transformed patient short and midterm prognosis. In this study, we aim to retrospectively analyze the postoperative outcomes of patients with carcinoid syndrome after heart valve surgery. Methods Data was retrospectively collected for patients referred to our institution for carcinoid heart disease and operated between 2013 and beginning of 2021. Results 8 patients underwent heart valve replacement with 1 having quadruple valve surgery, 3 patients had both tricuspid and pulmonary valves changed while 4 had only tricuspid valve replacements ; 3 patients had mechanical prostheses. 3 deaths occurred during the follow-up till date with 2 inside the perioperative period. No case of valvular complications was reported. Mean ICU and hospital stay were 9,4 days (range 1-39) and 23,5 days (range 10-52) respectively. 2 patients needed postoperative dialysis, 1 needed re-intubation and no patient required extracorporeal life support. The mean time period from diagnosis to valve surgery was 16,6 months (range 1-60). Follow-up (2-84 months) showed excellent postoperative clinical status with NYHA 1 in all patients. Conclusions Timely heart valve surgery in patients with close multidisciplinary monitoring is associated with good midterm survival rates and low perioperative valvular complications. Patients should be considered for surgery the soonest possible irrespective of the number of valves concerned as functional status improves drastically in most patients.
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RAMLUGUN et al. (2021) conducted an observational in Carcinoid heart disease (n=8). Surgical heart valve replacement was evaluated on Postoperative mortality and clinical status. Surgical valve replacement in 8 carcinoid heart disease patients resulted in 3 deaths (2 perioperative), 0% valvular complications, and NYHA class 1 status in survivors at 2-84 months.
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