Key result
Bibliometric analysis of 100 primary-care hypertension publications (12,214 citations) identified 6 thematic clusters with limited focus on real-world primary-care implementation.
Why the study?
Masked and white-coat hypertension are frequently missed in routine office-based assessment, and out-of-office monitoring is inconsistently implemented in primary care. No bibliometric study had mapped the global research landscape on these phenotypes within the primary care context.
Answers are grounded in this paper and cite their sources.
This bibliometric analysis demonstrates that while the diagnostic evidence base for masked and white-coat hypertension is mature, literature on real-world primary-care implementation and research outside high-income hubs remains underdeveloped.
Masked and white-coat hypertension are two clinically important blood pressure phenotypes that are frequently missed in routine office-based assessment, yet their detection depends heavily on out-of-office monitoring that is inconsistently implemented in primary care. Despite growing clinical interest, no bibliometric study has specifically mapped the global research landscape on these phenotypes within the primary care context. This study analyzed 100 publications indexed in the Web of Science Core Collection between 2000 and 2025 using a structured topic search combining terms for masked and white-coat hypertension with primary careâ"related terms. Data were cleaned and tabulated in Microsoft Excel and mapped using VOSviewer to characterize publication and citation trends, leading contributors, thematic structure, and collaboration networks. The included publications received a combined 12,214 citations, with output rising sharply between 2013 and 2020 before declining in recent years. The United States, United Kingdom, Spain, and Japan led global productivity, and research activity was concentrated among a small group of recurring authors and institutions organized into two largely separate collaboration clusters. Keyword co-occurrence analysis identified six thematic clusters centered on diagnostic phenotyping, blood pressure measurement methodology, and cardiovascular risk, with comparatively limited representation of primary-care implementation themes. Citation analysis showed that major guideline and scientific-statement documents, rather than primary-care-specific outcome studies, anchored the field's intellectual structure. These findings indicated a mature diagnostic evidence base alongside an underdeveloped literature on real-world primary-care implementation and international collaboration, particularly outside a small number of high-income research hubs, pointing to clear priorities for future research.
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Alazwari et al. (2026) studied Masked and white-coat hypertension in primary care (n=100). Bibliometric analysis using VOSviewer and Microsoft Excel was evaluated on Publication and citation trends, leading contributors, thematic structure, and collaboration networks. Bibliometric analysis of 100 primary-care hypertension publications (12,214 citations) identified 6 thematic clusters with limited focus on real-world primary-care implementation.
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