Key result
Modified stylet-guided LBBAP achieves ~100% procedural success and shortens QRS duration with zero complications.
Why the study?
The feasibility of a novel stylet-guided modified probe technique using 3D septal modeling for left bundle branch area pacing required evaluation.
Is the modified stylet-guided probe technique feasible and safe for achieving left bundle branch area pacing in patients with symptomatic bradycardia?
Observational (n=10)
No
Is the modified stylet-guided probe technique feasible and safe for achieving left bundle branch area pacing in patients with symptomatic bradycardia?
Answers are grounded in this paper and cite their sources.
This small retrospective feasibility study demonstrates that using a standard straight guidewire as a probe for 3D septal modeling simplifies left bundle branch area pacing with a 100% success rate, stable 3-month lead parameters, and no complications.
Objective To evaluate the feasibility of the modified probe technique for cardiac physiologic pacing (CPP). Method A retrospective analysis was conducted on symptomatic bradycardia patients undergoing CPP via the modified probe technique at the First Affiliated Hospital of Harbin Medical University (July–September 2024). The technique uses three‐dimensional (3D) septal modeling: A straight guidewire is first positioned at the optimal septal pacing site to guide ventricular lead implantation. Baseline data (past medical history, QRS duration, echocardiography) were collected. Intraoperative variables (bundle branch potentials, Sti‐LVAT, pacing threshold, impedance), postoperative complications (from EMR), and follow‐up threshold/impedance were recorded. Results This study included 10 patients (60% male; mean age 68 ± 10.84 years) with atrioventricular block or sick sinus syndrome. LBBAP was successful in all cases, with Sti‐LVAT ≤ 80 ms in 8 patients and 80–100 ms in 2. Postimplantation QRS duration significantly decreased (111.6 ± 27.29 ms vs. 130.6 ± 30.41 ms). No complications such as ventricular septal perforation, right bundle branch injury, electrode dislocation, and pericardial effusion were observed in this group. At 3 months, most pacing thresholds remained < 1.5 V; lead impedance decreased intraoperatively and stabilized thereafter. No complications occurred. Conclusion The modified probe method uses the original standard straight wire as a probe to conduct left bundle branch area pacing, which simplifies the surgical process of physiological pacing and improves the controllability of intraoperative operation. The parameters of the lead are stable during the follow‐up period, and the clinical application is feasible.
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Sheng et al. (2026) conducted an observational in Symptomatic bradycardia (atrioventricular block or sick sinus syndrome) (n=10). Modified stylet-guided probe technique for left bundle branch area pacing (LBBAP) was evaluated on Procedural success of left bundle branch area pacing (LBBAP) and postimplantation QRS duration reduction. The modified stylet-guided LBBAP technique achieved 100% procedural success and decreased QRS duration from 130.6 ± 30.41 ms to 111.6 ± 27.29 ms with no complications.
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