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October 1, 2021European Heart JournalOpen Access

LBBP achieves ~98% implantation success with favorable electrical parameters and rare lead dislodgement.

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Why the study?

Left Bundle Branch Pacing (LBBP) offers physiologic ventricular activation and better electrical parameters than His bundle pacing, but its feasibility and technical outcomes in daily clinical practice require evaluation.

Population

132 patients with standard indication for pacing including AV block, SND, AF, HF, and lead revision

Comparison

LBBP as first choice or after unsatisfactory His bundle pacing

Design

Single-centre cohort study

Follow-up

1 month in-clinic followed by remote monitoring

Key result

Left bundle branch pacing was successfully implanted in 97.7% of patients with standard pacing indications, demonstrating favorable electrical parameters and a 2.2% lead dislodgement rate.

Authors

LMLina MarcantoniOspedale Santa Maria della Misericordia di RovigoGPG. PastoreOspedale Santa Maria della Misericordia di RovigoEBEnrico BaraccaOspedale Santa Maria della Misericordia di Rovigo

Discussion

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Overview

LBBP implantation appears feasible in standard indications; leaves open need for randomized outcome trials versus conventional pacing.

Study Design

Type

Cohort (n=132)

Multicenter

No

Structured PICO

P
Population
132 patients (mean age 79 years, 45.5% female) with standard indications for pacing who underwent left bundle branch pacing.
E
Exposure
Left Bundle Branch Pacing (LBBP) using 3830 4Fr lumenless lead (107 cases) or stylet-driven 6Fr leads (25 cases), with the lead placed deeply intraseptal aiming to pace the left bundle.
O
Outcome
Feasibility and technical outcomes (successful implantation, electrical parameters, paced QRS duration, and lead dislodgement)surrogate

Left bundle branch pacing is a highly feasible and safe technique in routine clinical practice, achieving physiological ventricular activation with significant QRS narrowing and low complication rates.

Cite This Study

Marcantoni et al. (2021) conducted a cohort in Standard indication for pacing (n=132). Left Bundle Branch Pacing (LBBP) was evaluated on Successful implantation in the left bundle. Left bundle branch pacing was successfully implanted in 97.7% of patients with standard pacing indications, demonstrating favorable electrical parameters and a 2.2% lead dislodgement rate.

synapsesocial.com/papers/6aab93df20f4ead289cc699ehttps://doi.org/10.1093/eurheartj/ehab724.0685
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