Dual-imaging assessment of Hertz contact intravascular lithotripsy in a complex calcified lesion

Q: What is the clinical evidence from this study?

Study design: Case Report. Population: Severely calcified left anterior descending coronary artery lesion in multivessel coronary artery disease (n=1). Intervention: LithiX™ Hertz Contact Intravascular Lithotripsy (L-IVL) System. Primary outcome: Calcium fracture modification and stent expansion (minimal stent area).

Marta Bujak; Marek Milewski; Wojciech Wojakowski; Paweł M. Gąsior

doi:10.5603/cj.108903

February 5, 2026Cardiology JournalOpen Access

Dual-imaging assessment of Hertz contact intravascular lithotripsy in a complex calcified lesion

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Key result

LithiX Hertz Contact IVL achieves extensive calcium fracture and optimal stent expansion in calcified LAD.

n=1

Key Points

To evaluate the efficacy and fracture morphology of the novel LithiX Hertz Contact Intravascular Lithotripsy System in treating a severely calcified coronary artery lesion using dual-modality intravascular imaging.
Case study of a 66-year-old male with multivessel coronary artery disease undergoing staged percutaneous coronary intervention for a long, severely calcified left anterior descending artery lesion.
LithiX 3.0 × 14 mm balloon inflations (13 total inflations across 5, 8, and 12 atm) were delivered and assessed pre- and post-dilation using high-definition intravascular ultrasound and optical coherence tomography prior to drug-eluting stent implantation.
Dual imaging demonstrated extensive calcium modification, including deep-layered medial fractures and surface disruptions across thick, nodular, and circumferential calcium (> 270° arc), expanding the baseline minimal lumen area of 1.98 mm2.
Three drug-eluting stents were successfully deployed with final optical coherence tomography confirming full apposition, no edge dissection or residual stenosis, and minimal stent areas of 8.2 mm2 proximally and 5.1 mm2 distally.

Study Design

Type

Case Report (n=1)

Multicenter

No

PICO

P

Population

A 66-year-old man with multivessel coronary artery disease and a severely calcified left anterior descending artery lesion who declined surgical revascularization and underwent staged percutaneous coronary intervention.

I

Intervention / Comparator

LithiX™ Hertz Contact Intravascular Lithotripsy (L-IVL) System (3.0 × 14 mm balloon with 13 escalating inflations (5, 8, 12 atm))

O

Primary Outcome

Calcium fracture modification and stent expansion (minimal stent area)

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Implication

May enable stent expansion in severe coronary calcium; hypothesis-generating for novel Hertz contact IVL pending prospective trials.

Abstract

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Cite This Study

Bujak et al. (2026) conducted a case report in Severely calcified left anterior descending coronary artery lesion in multivessel coronary artery disease (n=1). LithiX™ Hertz Contact Intravascular Lithotripsy (L-IVL) System was evaluated on Calcium fracture modification and stent expansion (minimal stent area). The LithiX Hertz Contact Intravascular Lithotripsy system achieved extensive calcium fracture and optimal stent expansion (MSA 8.2 mm² proximally and 5.1 mm² distally) in a calcified LAD lesion.

synapsesocial.com/papers/6af0e9f0de503f3774140b06 https://doi.org/10.5603/cj.108903

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Dual-imaging assessment of Hertz contact intravascular lithotripsy in a complex calcified lesion

Key Points

Study Design

PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Dual-imaging assessment of Hertz contact intravascular lithotripsy in a complex calcified lesion

Key Points

Study Design

PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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