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Introduction: The success of an endodontic treatment depends on effective disinfection and complete sealing of root canal.The irrigants that are currently used in the field of endodontics have certain limitations, so the quest for an ideal root canal irrigant continues.Nowadays, the use of herbal extracts such as Fennel seed extract is used for their potent antimicrobial activity and less side effects.Objective: This study aimed to evaluate the antimicrobial efficacy of fennel seed extract with 2% chlorhexidine and 3% sodium hypochlorite against Enterococcus faecalis.Materials and method: The antimicrobial efficacy of Fennel seed extract was analysed with different concentration (50,100mg/ml) with 2% chlorhexidine and 3% sodium hypochlorite using the agar well-diffusion method.Minimum inhibitory concentration of the active extract was determined by the broth dilution assay.Result: Fennel seed extract at 50 and 100 percent concentrations is somewhat more effective against microbes than Sodium hypochlorite and chlorhexidine at 3% and 2%, respectively.Conclusion: When compared to sodium hypochlorite and chlorhexidine, fennel seed extract exhibits somewhat greater antibacterial effectiveness against E. faecalis within the limitations.Hence, fennel seed extract shows promise as an irrigant for teeth.
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