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The study aimed to optimize preoperative modeling and the individualized selection of surgical treatment for genital prolapse in women of childbearing age.Materials and methods: A retrospective-prospective descriptive comparative analysis of clinical and functional data from 85 fertile women (Group 1: n=45 with connective tissue dysplasia markers; Group 2: n=40 without manifest CTD) was conducted. Anatomical defects were quantified using the international POP-Q system, levator muscle tone was evaluated via perineometry and 3D/4D pelvic floor ultrasound, and systemic connective tissue dysplasia was assessed using clinical risk scores.Results: Standardized objective quantification using POP-Q, integration of obstetric history, levator defect scoring, and metabolic/CTD markers allowed for the development of a predictive mathematical risk matrix. Custom laparoscopic reconstructive techniques (pectopexy and laparoscopic sacrocolpopexy with autologous/mesh organ-preserving repair) yielded 95.6% 2-year anatomical success compared to 77.5% in standard vaginal repair.
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Kurbanbaev et al. (2026) studied this question.
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