Key result
Perioperative CPR yields ~80% immediate survival, with normalized LVEF at follow-up.
Why the study?
Perioperative cardiac arrest and life-threatening ventricular arrhythmias are critical anaesthetic emergencies associated with substantial morbidity and mortality, prompting this description of presentation, resuscitation, early outcomes, and potential contributing factors across diverse operative settings.
Case Report (n=5)
This five-patient case series highlights that prompt cardiopulmonary resuscitation and structured follow-up can result in immediate survival and normalization of left ventricular ejection fraction within 4–5 months following perioperative cardiac arrest and ventricular arrhythmias.
Answers are grounded in this paper and cite their sources.
Rapid rhythm-directed resuscitation may aid perioperative arrest survival; leaves open confirmation in larger prospective cohorts.
Background Perioperative cardiac arrest and life-threatening ventricular arrhythmias are critical anaesthetic emergencies associated with substantial morbidity and mortality. The study describes five cardiovascular emergencies across diverse operative settings, highlighting presentation, resuscitation, early outcomes and potential contributing factors. Case presentations Five patients aged 21–55 years experienced severe perioperative cardiovascular events. A man undergoing open hernioplasty for a strangulated inguinal hernia under spinal anaesthesia developed bradycardia followed by ventricular tachycardia (VT). A woman with Glanzmann thrombasthenia developed haemorrhagic shock and pulseless electrical activity during laparotomy. A patient with severe preeclampsia and anaemia experienced a fatal cardiac event during post-caesarean re-exploration. A man undergoing thoracic spine surgery developed post-induction collapse with subsequently documented VT. A postpartum patient with uterine inversion developed pulseless VT. Cardiopulmonary resuscitation was reported in all five cases. Four patients survived the immediate event; one maternal death occurred. Rhythm and medication documentation varied across cases. Recommendations: Early identification of cardiovascular instability, continuous haemodynamic monitoring, and prompt rhythm-directed resuscitation are essential for improving perioperative outcomes. Preoperative risk assessment, availability of emergency equipment and blood products, effective multidisciplinary coordination, and structured post-resuscitation care are recommended to enhance patient safety. Conclusion Intraoperative cardiac events included cardiac arrest, and all affected patients were successfully resuscitated, highlighting the importance of early recognition, prompt intervention, and effective perioperative resuscitation strategies. Postoperative echocardiography was performed to assess cardiac function, followed by continued clinical monitoring. During follow-up evaluations conducted approximately 4–5 months after surgery, repeat echocardiography demonstrated improvement in cardiac function, particularly left ventricular ejection fraction, which had returned to within normal limits. These findings highlight the importance of timely resuscitation, comprehensive postoperative cardiac assessment, and structured long-term follow-up in evaluating myocardial recovery and favourable cardiovascular outcomes following life-threatening intraoperative cardiac events.
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Rajasekhar et al. (2026) conducted a case report in Perioperative cardiac arrest and life-threatening ventricular arrhythmias (n=5). Cardiopulmonary resuscitation and perioperative cardiovascular emergency management was evaluated on Immediate survival following perioperative cardiac arrest and ventricular arrhythmias. Cardiopulmonary resuscitation for perioperative cardiac arrest or ventricular arrhythmias resulted in 80% immediate survival (4/5 patients) and normalized LVEF at 4-5 months.
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