Key result
Pulse oximetry screening in 11,094 newborns at a Portuguese tertiary hospital identified 0 cases of critical congenital heart disease, yielding a 0% positive predictive value and 0.5% false-positive rate.
Why the study?
Does neonatal pulse oximetry screening improve the detection of critical congenital heart disease in newborns at a tertiary hospital in Portugal?
Does neonatal pulse oximetry screening improve the detection of critical congenital heart disease in newborns at a tertiary hospital in Portugal?
Answers are grounded in this paper and cite their sources.
This editorial highlights that universal neonatal pulse oximetry screening for critical congenital heart disease yielded zero CCHD diagnoses over five years at a Portuguese tertiary hospital with advanced prenatal diagnostics, underscoring the need for formal national cost-effectiveness and stratified validation studies.
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Rato et al. (2026) conducted an editorial in Critical congenital heart disease (CCHD) (n=11,094). Pulse oximetry (POx) screening was evaluated on Detection of critical congenital heart disease (CCHD). Pulse oximetry screening in 11,094 newborns at a Portuguese tertiary hospital identified 0 cases of critical congenital heart disease, yielding a 0% positive predictive value and 0.5% false-positive rate.
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