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A 54-year-old man with back pain showed lytic vertebral lesions on MRI. 18 F-FDG PET/CT revealed an FDG-avid thyroid primary, skeletal metastases, and a relatively low FDG-avid right renal lesion. Thyroid histopathology confirmed follicular carcinoma. Post-thyroidectomy radioiodine scan demonstrated intense uptake in both skeletal and renal lesions. Biopsy from the renal lesion confirmed renal metastasis. Renal involvement in differentiated thyroid cancer is rare and may demonstrate concordant FDG and radioiodine avidity.
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Rahman et al. (2026) studied this question.
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