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Postoperative nausea and vomiting (PONV) can interfere with oral intake and early recovery after bimaxillary orthognathic surgery. This single-centre, prospective, parallel-group, outcome-assessor-blinded randomized controlled trial evaluated a postoperative PONV risk-stratified nursing pathway in 180 adults undergoing Le Fort I osteotomy combined with bilateral sagittal split osteotomy. Patients were allocated 1:1 to usual care or risk-stratified nursing. Surgery, anaesthesia and postoperative analgesia followed the same institutional principles in both groups. The intervention comprised Apfel score-based symptom surveillance, structured nursing management of PONV, and a readiness-based stepwise oral-intake pathway after the routine 6-hour postoperative fasting period. The primary outcome was the 24-hour Quality of Recovery-15 (QoR-15) score. Overall 0-hour to 24-hour PONV incidence did not differ significantly between the risk-stratified nursing and usual-care groups (46.7% versus 51.1%; relative risk, 0.91; 95% CI: 0.68–1.23; P =0.551). Moderate-to-severe nausea was less frequent with risk-stratified nursing (12.2% versus 27.8%; relative risk, 0.44; 95% CI: 0.23–0.84; P =0.009). The intervention group achieved successful oral intake earlier [7.2 (6.7, 7.8) versus 7.8 (7.4, 8.3) h; P <0.001], had greater 6-hour to 12-hour and 0-hour to 24-hour intake, and fewer PONV-related feeding interruptions. The adjusted between-group difference in 24-hour QoR-15 was 5.9 points (95% CI: 3.5–8.2; P <0.001). A postoperative PONV risk-stratified nursing pathway improved symptom burden, oral intake recovery, and patient-reported early recovery after bimaxillary orthognathic surgery.
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王丹妮 et al. (2026) studied this question.
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