Vaccination survey during pregnancy: five-year trend on vaccine coverage for Tdap, HBV, influenza and COVID-19 and acceptance of a future group B Streptococcus vaccine in Brazil

Brazil has a robust national immunization program (NIP) for pregnant people, but recent trends in vaccine hesitancy have raised concerns on coverage rates and acceptance of future vaccines, such as Group B Streptococcus (GBS) vaccine currently in late stage of development. Here we determined coverage of four vaccines recommended during pregnancy and assessed the perception of a future GBS vaccine among 1,449 pregnant individuals in Rio de Janeiro, Brazil, based on data from a self-reported single site survey study. Vaccine coverage for Influenza was highest (75.2%), followed by Tdap (69.9%), COVID-19(68.5%) and HBV (57.6%). While 96.6% were willing to take a future GBS vaccine, only 19.9% were aware of GBS perinatal risks. No sociodemographic variable was associated with vaccine coverage or acceptance, except for the association of marriage with individuals not vaccinated for Tdap ( p = 0.0207). Our findings show vaccine coverage varied over time for Influenza, Tdap, COVID-19 and HBV vaccines, but acceptance of a future GBS vaccine was uniformly high throughout the study; and no sociodemographic aspect was associated with vaccine acceptance in the population analysed.