Oral Health‐Related Quality of Life, Perceived Stress, and Well‐Being in Oral Lichen Planus Subtypes

Objective Oral lichen planus (OLP) is a chronic inflammatory mucosal disease with reticular and erosive clinical subtypes. This study aimed to compare oral health‐related quality of life (OHRQoL), stress, and general well‐being between participants with reticular OLP, erosive OLP, and healthy controls. Material and Methods In this single‐center cross‐sectional study, healthy controls ( n = 20) and patients with reticular ( n = 20) or erosive OLP ( n = 20) completed the OHIP‐G14, PSS‐10, and WHO‐5‐questionnaires, and group differences were evaluated. Results Patients with OLP reported significantly poorer OHRQoL than controls (OHIP‐G14 total score: 13.18 ± 10.01 vs. 2.85 ± 6.54; p < 0.001). Significant group differences were observed across all OHIP‐G14 subdomains. Erosive OLP showed higher scores than reticular OLP across domains, though subtype differences were not significant. In both OLP groups, the highest mean scores were observed for physical pain and psychological discomfort. No significant between‐group differences were observed for PSS‐10 or WHO‐5 (all p ≥ 0.259). Interpretation is limited by differences in baseline characteristics between groups. Conclusion Patients with OLP reported poorer OHRQoL than healthy controls, whereas differences between reticular and erosive OLP were not significant. The findings suggest that oral‐specific and generic patient‐reported outcome measures capture complementary aspects of patient experience, with OHIP‐G14 reflecting oral disease‐specific burden in OLP.