Why the study?
In advanced Fabry cardiomyopathy with extensive septal late gadolinium enhancement, identifying an optimal site for leadless pacemaker implantation to minimize repeated fixation attempts is needed.
Population
Fabry disease with permanent atrial fibrillation and bradycardia
Answers are grounded in this paper and cite their sources.
Preprocedural CMR may guide leadless pacemaker placement in Fabry cardiomyopathy to reduce fixation attempts; hypothesis-generating and should not yet change practice.
In advanced Fabry cardiomyopathy, preprocedural cardiac magnetic resonance imaging may reveal a lower septal region spared from otherwise extensive septal late gadolinium enhancement. This information, combined with pre‐fixation electrical mapping, may help identify an optimal site for leadless pacemaker implantation and minimize repeated fixation attempts.
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Saito et al. (2026) studied this question.
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