Key result
OCT identifies nonobstructive LIMA graft dissection and safely guides stent deferral in a case.
Why the study?
Angiographic narrowing of a LIMA bypass graft does not always reflect atherosclerotic progression, as chronic or spontaneous LIMA graft dissection may mimic atherosclerotic stenosis and can be identified using optical coherence tomography.
Case Report (n=1)
Intravascular optical coherence tomography can distinguish chronic or spontaneous LIMA bypass graft dissection from atherosclerotic stenosis, guiding appropriate stent deferral and preventing potential graft compromise from inadvertent false-lumen stenting.
Answers are grounded in this paper and cite their sources.
May allow safe stent deferral in ambiguous graft lesions; leaves open generalizability and need for prospective validation.
Angiographic narrowing of a left internal mammary artery (LIMA) bypass graft does not always reflect atherosclerotic progression. Chronic or spontaneous LIMA graft dissection may be identified using optical coherence tomography (OCT). A patient with severe multivessel coronary disease and a history of coronary stenting and triple coronary artery bypass grafting presented with non-ST-elevation myocardial infarction. Coronary angiography demonstrated critical left main-left circumflex disease, extensive left anterior descending artery in-stent restenosis, an occluded venous graft, and eccentric mid-LIMA narrowing. Urgent native-vessel revascularization restored Thrombolysis in Myocardial Infarction (TIMI) grade 3 flow and relieved the patient's symptoms. During staged LIMA assessment 6 days later, OCT was performed using a Dragonfly OpStar imaging catheter. OCT identified the entry of a longitudinal intimal flap separating the true and false lumens over a long segment, without significant atherosclerosis in the imaged segment. The operators interpreted this "double-barrel" configuration as a nonobstructive dissection of presumed chronicity. Preserved LIMA flow and clinical stability supported stent deferral; the patient remained asymptomatic and with preserved ejection fraction at the 2-month follow-up visit. This report offers important lessons for interventionalists: intravascular imaging can distinguish dissection from apparent atherosclerotic stenosis and significantly drive further management. Inadvertent false-lumen stenting could expand the false channel, compress the true lumen, and compromise graft perfusion. OCT clearly elucidated lesion morphology and supported clinical restraint; however, it did not independently establish dissection age or an exact mechanism of dissection.
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Borovac et al. (2026) conducted a case report in Left internal mammary artery (LIMA) bypass graft dissection presenting with non-ST-elevation myocardial infarction (n=1). Optical coherence tomography (OCT)-guided stent deferral was evaluated on Asymptomatic status with preserved ejection fraction at 2-month follow-up. Optical coherence tomography identified a nonobstructive LIMA graft dissection and guided stent deferral, leaving the patient asymptomatic at 2-month follow-up.
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