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In originally issued as document our work, the goal was to study the pathological manifestations of angio and neuromyopathy as a result of chronic exposure to therapeutic doses of opioid analgesic and the possibility of simultaneous correction of these changes with the drug pentoxifylline in the early stages restrukturizatsii changes in the retinal layers. The goal was achieved through the use of histological techniques retinal. Histological preparations were made by the conventional method with the use of dyes, hematoxylin, eosin, and (adhan) by the method Heidenhaina.The results of the study in the future will form a pathological base, with clinical guidelines that to unwanted simultaneous use of pentoxifylline and opob. These data can be used for the comparative performance, relative to the processes of the dynamics of increase of pathological changes in the layers of the retina during short and long term exposure of low doses of opioids and correction of these changes with the drug pentoxifylline on early and psdn terms of opioid effect. The above will further provide the opportunity to establish the most optimal timeframe for which a characteristic set of pathological manifestations elementary phenomena ungeneralised in the layers of the retina that can best be coregular influence.
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Paltov et al. (2020) studied this question.
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