A Review of Platelet-Rich Plasma as Treatment for Partial Elbow Ulnar Collateral Ligament Tears

Platelet-rich plasma injections are increasingly utilized for partial-thickness ulnar collateral ligament tears in throwing athletes. This narrative review evaluates platelet-rich plasma's efficacy, safety, and cost-effectiveness for partial ulnar collateral ligament tears using literature from 2020 to 2026. A systematic search identified four studies, including cohorts and an economic simulation model. The largest cohort demonstrated that 60% of athletes with partial tears returned to play when platelet-rich plasma was combined with rehabilitation. Smaller case series reported successful return to play with similar treatment, though limited by a lack of comparison groups and small sample sizes. Complications included ulnar nerve dysfunction, particularly in athletes with preexisting nerve instability. Early surgery was often more cost-effective for long-term career durability. Current evidence suggests platelet-rich plasma alongside rehabilitation may benefit select athletes with partial ulnar collateral ligament injuries but is limited by retrospective designs, heterogeneous protocols, and inconsistent outcome measures. Future research is needed regarding patient selection and standardized treatment protocols.